Academic Enrichment: Undergraduate research project (6 points) — Class of 2028

 Joining Dr. Daniel Ashley’s computational chemistry lab at Spelman College marked my first formal entry into computational research, allowing me to explore the intersection of chemistry, neuroscience, and health equity. In this lab, I focus on molecular modeling related to melanin and neurological function, particularly examining how metal ions interact with biomolecules through inorganic chemistry frameworks. This experience introduced me to computational tools such as molecular visualization and modeling software, expanding my understanding of how theoretical chemistry can be used to investigate biologically and clinically relevant questions.

One of the strongest aspects of this research experience has been learning how abstract chemical principles translate into meaningful biological insight. Modeling molecular structures required precision, patience, and iterative problem-solving, reinforcing the importance of accuracy and reproducibility in scientific research. I also gained exposure to collaborative scientific inquiry through lab discussions, where hypotheses were refined collectively and findings were contextualized within existing literature. This process strengthened my ability to communicate complex ideas clearly and to engage critically with scientific data.

From a reflective standpoint, this experience challenged me to step outside my comfort zone and embrace a new methodological approach to research. Coming from a background rooted in biology and public health, learning computational chemistry required adaptability and intellectual humility. However, this challenge ultimately deepened my confidence as a researcher and sharpened my analytical thinking. I began to recognize how computational methods can serve as powerful tools for addressing questions that are difficult to study experimentally alone.

This research also reinforced my interest in pursuing interdisciplinary work as a future physician-scientist. Studying melanin through a chemical and neurological lens has important implications for understanding neurodegenerative processes and health disparities, particularly in conditions that disproportionately affect marginalized communities. The experience connected directly to my broader academic goals in neuroscience and health equity, illustrating how foundational science informs translational and clinical outcomes.

Moving forward, I plan to continue developing my computational skill set and applying these methods to more complex biological systems. This experience has solidified my commitment to research that bridges disciplines and addresses real-world health challenges, and it has strengthened my aspiration to pursue an MD-PhD focused on neuroscience and equitable scientific innovation.

By: Kandace N. Bryant